Lipopolysaccharide-induced inflammation

Castellano G, Stasi A, Intini A, et al. Endothelial dysfunction and renal fibrosis in endotoxemia-induced oliguric kidney injury: possible role of LPS-binding protein. Crit Care. 2014;18(5):520. doi:10.1186/s13054-014-0520-2

Chen D, Sahin A, Kam WR, Liu Y, Darabad RR, Sullivan DA. Influence of lipopolysaccharide on proinflammatory gene expression in human corneal, conjunctival and meibomian gland epithelial cells. Ocul Surf. 2018;16(3):382-389. doi:10.1016/j.jtos.2018.05.003

Collodel G, Castellini C, del Vecchio MT, et al. Effect of a bacterial lipopolysaccharide treatment on rabbit testis and ejaculated sperm. Reprod Domest Anim. 2012;47(3):372-378. doi:10.1111/j.1439-0531.2011.01882.x

Domínguez-Rivas E, Ávila-Muñoz E, Schwarzacher SW, Zepeda A. Adult hippocampal neurogenesis in the context of lipopolysaccharide-induced neuroinflammation: A molecular, cellular and behavioral review. Brain Behav Immun. 2021;97:286-302. doi:10.1016/j.bbi.2021.06.014

Maniar-Hew K, Clay CC, Postlethwait EM, Evans MJ, Fontaine JH, Miller LA. Innate immune response to LPS in airway epithelium is dependent on chronological age and antecedent exposures. Am J Respir Cell Mol Biol. 2013;49(5):710-720. doi:10.1165/rcmb.2012-0321OC

Mao M, Zhou Z, Sun M, Wang C, Sun J. The dysfunction of parvalbumin interneurons mediated by microglia contributes to cognitive impairment induced by lipopolysaccharide challenge. Neurosci Lett. 2021;762:136133. doi:10.1016/j.neulet.2021.136133

LPS induces hippocampus-dependent memory and working memory impairment.

Metukuri MR, Reddy CMT, Reddy PRK, Reddanna P. Bacterial LPS-mediated acute inflammation-induced spermatogenic failure in rats: role of stress response proteins and mitochondrial dysfunction. Inflammation. 2010;33(4):235-243. doi:10.1007/s10753-009-9177-4

Mouton PR, Kelley-Bell B, Tweedie D, et al. The effects of age and lipopolysaccharide (LPS)-mediated peripheral inflammation on numbers of central catecholaminergic neurons. Neurobiol Aging. 2012;33(2):423.e27-36. doi:10.1016/j.neurobiolaging.2010.09.025

Murtaj V, Belloli S, Di Grigoli G, et al. Age and sex influence the neuro-inflammatory response to a peripheral acute LPS challenge. Front Aging Neurosci. 2019;11:299. doi:10.3389/fnagi.2019.00299

Nejsum LN, Piec A, Fijak M, et al. Systemic LPS induces toll-like receptor 3 (TLR3) expression and apoptosis in testicular mouse tissue. Cell Tissue Res. 2019;378(1):143-154. doi:10.1007/s00441-019-03022-w

Norata GD, Tibolla G, Seccomandi PM, Poletti A, Catapano AL. Dihydrotestosterone decreases tumor necrosis factor-alpha and lipopolysaccharide-induced inflammatory response in human endothelial cells. J Clin Endocrinol Metab. 2006;91(2):546-554. doi:10.1210/jc.2005-1664

O’Bryan MK, Schlatt S, Phillips DJ, de Kretser DM, Hedger MP. Bacterial lipopolysaccharide-induced inflammation compromises testicular function at multiple levels in vivo. Endocrinology. 2000;141(1):238-246. doi:10.1210/endo.141.1.7240

Reddy MM, Mahipal SVK, Subhashini J, et al. Bacterial lipopolysaccharide-induced oxidative stress in the impairment of steroidogenesis and spermatogenesis in rats. Reprod Toxicol. 2006;22(3):493-500. doi:10.1016/j.reprotox.2006.03.003

Sano M, Komiyama H, Shinoda R, et al. NLRP3 inflammasome is involved in testicular inflammation induced by lipopolysaccharide in mice. Am J Reprod Immunol. 2022;87(4):e13527. doi:10.1111/aji.13527

Wang F, Liu W, Jiang Q, et al. Lipopolysaccharide-induced testicular dysfunction and epididymitis in mice: a critical role of tumor necrosis factor alpha. Biol Reprod. 2019;100(3):849-861. doi:10.1093/biolre/ioy235

Wang G, Cheng S, Zhang S, Zhu Y, Xiao Y, Ju L. LPS impairs steroidogenesis and ROS metabolism and induces PPAR transcriptional activity to disturb estrogen/androgen receptor expression in testicular cells. Mol Biol Rep. 2020;47(2):1045-1056. doi:10.1007/s11033-019-05196-6

Wang H, Yang LL, Hu YF, et al. Maternal LPS exposure during pregnancy impairs testicular development, steroidogenesis and spermatogenesis in male offspring. PLoS One. 2014;9(9):e106786. doi:10.1371/journal.pone.0106786

Yang L, Zhou R, Tong Y, et al. Neuroprotection by dihydrotestosterone in LPS-induced neuroinflammation. Neurobiol Dis. 2020;140:104814. doi:10.1016/j.nbd.2020.104814

Zeng J, Zhào H, Liu Z, Zhang W, Huang Y. Lipopolysaccharide induces subacute cerebral microhemorrhages with involvement of nitric oxide synthase in rats. J Stroke Cerebrovasc Dis. 2018;27(7):1905-1913. doi:10.1016/j.jstrokecerebrovasdis.2018.02.044

Zhao X, Cao F, Liu Q, et al. Behavioral, inflammatory and neurochemical disturbances in LPS and UCMS-induced mouse models of depression. Behav Brain Res. 2019;364:494-502. doi:10.1016/j.bbr.2017.05.064

Zhou HS, Li M, Sui BD, et al. Lipopolysaccharide impairs permeability of pulmonary microvascular endothelial cells via Connexin40. Microvasc Res. 2018;115:58-67. doi:10.1016/j.mvr.2017.08.008