Related research by field

This bibliography consists of research that is not specifically about adverse effects of finasteride, but could inform explanation, diagnosis or treatment of post-finasteride syndrome.

Fields

See also: Related research: Special topics

Dermatology

Babbush KM, Andriano TM, Cohen SR. Anti-androgen therapy in hidradenitis suppurativa: finasteride for females. Clin Exp Dermatol. 2021 Jul 14. doi:10.1111/ced.14847 | PubMed

Camacho FM, García-Hernández MJ, Fernández-Crehuet JL. Value of hormonal levels in patients with male androgenetic alopecia treated with finasteride: better response in patients under 26 years old. Br J Dermatol. 2008 May. doi:10.1111/j.1365-2133.2008.08509.x | PubMed

Hatanaka T, Lulic Z, Mefo T, Booth C, Harrison E, Ong G. Change in hair growth-related gene expression profile in human isolated hair follicles induced by 5-alpha reductase inhibitors – dutasteride and finasteride – in the presence of testosterone. Singapore Med J. 2021 Jun 22. doi:10.11622/smedj.2021080 | PubMed

Keene S, Goren A. Therapeutic hotline. Genetic variations in the androgen receptor gene and finasteride response in women with androgenetic alopecia mediated by epigenetics. Dermatol Ther. 2011 Mar-Apr. doi:10.1111/j.1529-8019.2011.01407.x | PubMed

Motofei IG, Rowland DL, Baconi DL, et al. Androgenetic alopecia; drug safety and therapeutic strategies. Expert Opin Drug Saf. 2018. doi:10.1080/14740338.2018.1430765 | PubMed

[Comment] Ong G, Manyak M, Lulic Z. Letter to the Editor: androgenetic alopecia; drug safety and therapeutic strategies. Expert Opin Drug Saf. 2018 Jun. doi:10.1080/14740338.2018.1470744 | PubMed

[Comment] Motofei IG, Rowland DL. Response to the letter to the editor; Androgenetic alopecia; drug safety and therapeutic strategies. Expert Opin Drug Saf. 2018 Jun. doi:10.1080/14740338.2018.1470749 | PubMed

Wakisaka N, Taira Y, Ishikawa M, et al. Effectiveness of finasteride on patients with male pattern baldness who have different androgen receptor gene polymorphism. J Investig Dermatol Symp Proc. 2005 Dec. doi:10.1111/j.0022-202X.2005.10123.x | PubMed

Yamazaki M, Sato A, Toyoshima KE, et al. Polymorphic CAG repeat numbers in the androgen receptor gene of female pattern hair loss patients. J Dermatol. 2011 Jul. doi:10.1111/j.1346-8138.2010.01060.x | PubMed

Endocrinology, andrology and sexual medicine

Anawalt BD. Is Dihydrotestosterone a Classic Hormone? Endocr Rev. 2017 Jun 1. doi:10.1210/er.2017-00091 | PubMed

Baker RC, Bergeson RL, Yi YA, Ward EE, Morey AF. Dutasteride in the long-term management of stuttering priapism. Transl Androl Urol. 2020 Feb. doi:10.21037/tau.2019.07.15 | PubMed | PMC full text

Boehmer AL, Brinkmann AO, Nijman RM, et al. Phenotypic variation in a family with partial androgen insensitivity syndrome explained by differences in 5alpha dihydrotestosterone availability. J Clin Endocrinol Metab. 2001. doi:10.1210/jcem.86.3.7333 | PubMed

Borst SE, Yarrow JF, Conover CF, et al. Musculoskeletal and prostate effects of combined testosterone and finasteride administration in older hypogonadal men: a randomized, controlled trial. Am J Physiol Endocrinol Metab. 2014 Feb 15. doi:10.1152/ajpendo.00592.2013 | PubMed | PMC full text

Borst SE, Yarrow JF, Fernandez C, et al. Cognitive effects of testosterone and finasteride administration in older hypogonadal men. Clin Interv Aging. 2014 Aug 12. doi:10.2147/CIA.S61760 | PubMed | PMC full text

Karakas SE, Surampudi P. New Biomarkers to Evaluate Hyperandrogenemic Women and Hypogonadal Men. Adv Clin Chem. 2018. doi:10.1016/bs.acc.2018.06.001 | PubMed

Rachid-Filho D, Cavalcanti AG, Favorito LA, Costa WS, Sampaio FJ. Treatment of recurrent priapism in sickle cell anemia with finasteride: a new approach. Urology. 2009 Nov. doi:10.1016/j.urology.2009.04.071 | PubMed

Sasaki G, Ishii T, Hori N, Amano N, Homma K, Sato S, Hasegawa T. Effects of pre- and post-pubertal dihydrotestosterone treatment on penile length in 5α-reductase type 2 deficiency. Endocr J. 2019 Sep 28. doi:10.1507/endocrj.EJ19-0111 | PubMed

Schulster M, Bernie AM, Ramasamy R. The role of estradiol in male reproductive function. Asian J Androl. 2016 May-Jun. doi:10.4103/1008-682X.173932 | PubMed | PMC full text

Swerdloff RS, Dudley RE, Page ST, Wang C, Salameh WA. Dihydrotestosterone: Biochemistry, Physiology, and Clinical Implications of Elevated Blood Levels. Endocr Rev. 2017 Jun 1. doi:10.1210/er.2016-1067 | PubMed | PMC full text

Tut TG, Ghadessy FJ, Trifiro MA, Pinsky L, Yong EL. Long polyglutamine tracts in the androgen receptor are associated with reduced trans-activation, impaired sperm production, and male infertility. J Clin Endocrinol Metab. 1997 Nov. doi:10.1210/jcem.82.11.4385 | PubMed

Yamana K, Labrie F, Luu-The V. Human type 3 5α-reductase is expressed in peripheral tissues at higher levels than types 1 and 2 and its activity is potently inhibited by finasteride and dutasteride. Horm Mol Biol Clin Investig. 2010 Aug 1. doi:10.1515/HMBCI.2010.035 | PubMed

Genetics

See also: Androgen receptors and Research by field: Genetics

Buccitelli C, Selbach M. mRNAs, proteins and the emerging principles of gene expression control. Nat Rev Genet. 2020 Oct. doi:10.1038/s41576-020-0258-4 | PubMed

Ellis JA, Stebbing M, Harrap SB. Polymorphism of the androgen receptor gene is associated with male pattern baldness. J Invest Dermatol. 2001 Mar. doi:10.1046/j.1523-1747.2001.01261.x | PubMed

Grigorova M, Punab M, Kahre T, et al. The number of CAG and GGN triplet repeats in the Androgen Receptor gene exert combinatorial effect on hormonal and sperm parameters in young men. Andrology. 2017 May. doi:10.1111/andr.12344 | PubMed

Häggström S, Tørring N, Møller K, et al. Effects of finasteride on vascular endothelial growth factor. Scand J Urol Nephrol. 2002. doi:10.1080/003655902320131848 | PubMed

Hatanaka T, Lulic Z, Mefo T, Booth C, Harrison E, Ong G. Change in hair growth-related gene expression profile in human isolated hair follicles induced by 5-alpha reductase inhibitors – dutasteride and finasteride – in the presence of testosterone. Singapore Med J. 2021 Jun 22. doi:10.11622/smedj.2021080 | PubMed

Katharopoulos E, Sauter K, Pandey AV, Flück CE. In silico and functional studies reveal novel loss-of-function variants of SRD5A2, but no variants explaining excess 5α-reductase activity. J Steroid Biochem Mol Biol. 2019 Jun. doi:10.1016/j.jsbmb.2019.01.017 | PubMed

Levy-Nissenbaum E, Bar-Natan M, Frydman M, Pras E. Confirmation of the association between male pattern baldness and the androgen receptor gene. Eur J Dermatol. 2005 Sep-Oct. PubMed

Lin ZM, Fan DD, Jin S, Liu ZL, Niu YN. Methylated CpG dinucleotides in the 5-α reductase 2 gene may explain finasteride resistance in benign prostatic enlargement patients. Asian J Androl. 2020 Nov 20. doi:10.4103/aja.aja_63_20 | PubMed

Lolli F, Pallotti F, Rossi A, Fortuna MC, Caro G, Lenzi A, Sansone A, Lombardo F. Androgenetic alopecia: a review. Endocrine. 2017 Jul. doi:10.1007/s12020-017-1280-y | PubMed

Medline Plus: SRD5A2 gene.

Samtani R, Bajpai M, Ghosh PK, Saraswathy KN. A49T, R227Q and TA repeat polymorphism of steroid 5 alpha-reductase type II gene and Hypospadias risk in North Indian children. Meta Gene. 2014 Dec 11. doi:10.1016/j.mgene.2014.11.003 | PubMed

Sasaki G, Ishii T, Hori N, Amano N, Homma K, Sato S, Hasegawa T. Effects of pre- and post-pubertal dihydrotestosterone treatment on penile length in 5α-reductase type 2 deficiency. Endocr J. 2019 Sep 28. doi:10.1507/endocrj.EJ19-0111 | PubMed

Stiles AR, Russell DW. SRD5A3: A surprising role in glycosylation. Cell. 2010 Jul 23. doi:10.1016/j.cell.2010.07.003 | 20655462 | PMC full text

Tirabassi G, Cignarelli A, Perrini S, et al. Influence of CAG Repeat Polymorphism on the Targets of Testosterone Action. Int J Endocrinol. 2015. doi:10.1155/2015/298107 | PubMed | Full text

Geriatrics

Borst SE, Yarrow JF, Conover CF, et al. Musculoskeletal and prostate effects of combined testosterone and finasteride administration in older hypogonadal men: a randomized, controlled trial. Am J Physiol Endocrinol Metab. 2014 Feb 15. doi:10.1152/ajpendo.00592.2013 | PubMed | PMC full text

Borst SE, Yarrow JF, Fernandez C, et al. Cognitive effects of testosterone and finasteride administration in older hypogonadal men. Clin Interv Aging. 2014 Aug 12. doi:10.2147/CIA.S61760 | PubMed | PMC full text

Na HR, Lee JW, Park SM, Ko SB, Kim S, Cho ST. Inappropriate sexual behaviors in patients with vascular dementia: possible response to finasteride. J Am Geriatr Soc. 2009 Nov. doi:10.1111/j.1532-5415.2009.02536.x | PubMed

Neuroendocrinology

Agis-Balboa RC, Guidotti A, Pinna G. 5α-reductase type I expression is downregulated in the prefrontal cortex/Brodmann’s area 9 (BA9) of depressed patients. Psychopharmacology (Berl). 2014 Sep. doi:10.1007/s00213-014-3567-5 | PubMed | PMC full text

Bali A, Jaggi AS. Multifunctional aspects of allopregnanolone in stress and related disorders. Prog Neuropsychopharmacol Biol Psychiatry. 2014 Jan 3. doi:10.1016/j.pnpbp.2013.09.005 | PubMed

Bortolato M, Devoto P, Roncada P, et al. Isolation rearing-induced reduction of brain 5α-reductase expression: relevance to dopaminergic impairments. Neuropharmacology. 2011 Jun. doi:10.1016/j.neuropharm.2011.01.013 | PubMed

Chen S, Gao L, Li X, Ye Y. Allopregnanolone in mood disorders: mechanism and therapeutic development. Pharmacol Res. 2021 May 18. doi:10.1016/j.phrs.2021.105682 | PubMed

Christian CA. Nucleus-specific modulation of phasic and tonic inhibition by endogenous neurosteroidogenesis in the murine thalamus. Synapse. 2020 May. doi:10.1002/syn.22144 | PubMed | PMC full text

Duong P, Tenkorang MAA, Trieu J, McCuiston C, Rybalchenko N, Cunningham RL. Neuroprotective and neurotoxic outcomes of androgens and estrogens in an oxidative stress environment. Biol Sex Differ. 2020 Mar 29. doi:10.1186/s13293-020-0283-1 | PubMed | PMC full text

Frau R, Bini V, Pes R, et al. Inhibition of 17α-hydroxylase/C17,20 lyase reduces gating deficits consequent to dopaminergic activation. Psychoneuroendocrinology. 2014 Jan. doi:10.1016/j.psyneuen.2013.09.014 | PubMed | PMC full text

Frau R, Mosher LJ, Bini V, et al. The neurosteroidogenic enzyme 5α-reductase modulates the role of D1 dopamine receptors in rat sensorimotor gating. Psychoneuroendocrinology. 2016. doi:10.1016/j.psyneuen.2015.09.014 | PubMed

Giatti S, Diviccaro S, Falvo E, Miguel Garcia-Segura L, Melcangi RC. Physiopathological role of the enzymatic complex 5α-reductase and 3α/β-hydroxysteroid oxidoreductase in the generation of progesterone and testosterone neuroactive metabolites. Front Neuroendocrinol. 2020. doi:10.1016/j.yfrne.2020.100836 | PubMed

Giatti S, Diviccaro S, Serafini MM, et al. Sex differences in steroid levels and steroidogenesis in the nervous system: Physiopathological role. Front Neuroendocrinol. 2020. doi:10.1016/j.yfrne.2019.100804PubMed

Giatti S, Garcia-Segura LM, Barreto GE, Melcangi RC. Neuroactive steroids, neurosteroidogenesis and sex. Prog Neurobiol. 2019. doi:10.1016/j.pneurobio.2018.06.007 | PubMed

Hill RA, Pompolo S, Jones ME, Simpson ER, Boon WC. Estrogen deficiency leads to apoptosis in dopaminergic neurons in the medial preoptic area and arcuate nucleus of male mice. Mol Cell Neurosci. 2004 Dec. doi:10.1016/j.mcn.2004.04.012 | PubMed

Kalakh S, Mouihate A. Enhanced remyelination during late pregnancy: involvement of the GABAergic system. Sci Rep. 2019 May 22. doi:10.1038/s41598-019-44050-4 | PubMed | PMC full text

Melcangi RC, Panzica GC. Allopregnanolone: state of the art. Prog Neurobiol. 2014 Feb. doi:10.1016/j.pneurobio.2013.09.005 | PubMed

Melcangi RC, Riva MA, Fumagalli F, Magnaghi V, Racagni G, Martini L. Effect of progesterone, testosterone and their 5 alpha-reduced metabolites on GFAP gene expression in type 1 astrocytes. Brain Res. 1996. doi:10.1016/0006-8993(95)01302-4 | PubMed

Meng Z, Rowlett JK. Self-administration of progesterone and synthetic neuroactive steroids by male rhesus monkeys. Drug Alcohol Depend. 2016 Aug 1. doi:10.1016/j.drugalcdep.2016.05.029 | PubMed | PMC full text

Misztal T, Młotkowska P, Marciniak E, Roszkowicz-Ostrowska K, Misztal A. Involvement of neurosteroids in the control of hypothalamic-pituitary-adrenal axis activity in pregnant sheep under basal and stressful conditions. Theriogenology. 2021 Aug 20. doi:10.1016/j.theriogenology.2021.08.026 | PubMed

Nasiri M, Nikolaou N, Parajes S, et al. 5α-Reductase Type 2 Regulates Glucocorticoid Action and Metabolic Phenotype in Human Hepatocytes. Endocrinology. 2015 Aug. doi:10.1210/en.2015-1149 | PubMed | PMC full text

Pinacho-Garcia LM, Valdez RA, Navarrete A, Cabeza M, Segovia J, Romano MC. The effect of finasteride and dutasteride on the synthesis of neurosteroids by glioblastoma cells. Steroids. 2020 Mar. doi:10.1016/j.steroids.2019.108556 | PubMed

Pinna G. Allopregnanolone, the Neuromodulator Turned Therapeutic Agent: Thank You, Next? Front Endocrinol (Lausanne). 2020 May 14. doi:10.3389/fendo.2020.00236 | PubMed | PMC full text

Samba Reddy D, Ramanathan G. Finasteride inhibits the disease-modifying activity of progesterone in the hippocampus kindling model of epileptogenesis. Epilepsy Behav. 2012 Sep. doi:10.1016/j.yebeh.2012.05.024 | PubMed

Scarduzio M, Panichi R, Pettorossi VE, Grassi S. Synaptic long-term potentiation and depression in the rat medial vestibular nuclei depend on neural activation of estrogenic and androgenic signals. PLoS One. 2013 Nov 12. doi:10.1371/journal.pone.0080792 | PubMed | PMC full text

Shen ZJ, Lu YL, Chen ZD, Chen F, Chen Z. Effects of androgen and ageing on gene expression of vasoactive intestinal polypeptide in rat corpus cavernosum. BJU Int. 2000 Jul. doi:10.1046/j.1464-410x.2000.00721.x | PubMed

Sun YH, Gao X, Tang YJ, Xu CL, Wang LH. Androgens induce increases in intracellular calcium via a G protein-coupled receptor in LNCaP prostate cancer cells. J Androl. 2006 Sep-Oct. doi:10.2164/jandrol.106.000554 | PubMed

Tesone AJ, Regueira E, Canosa LF, Ceballos NR. 5α-Reductase, an enzyme regulating glucocorticoid action in the testis of Rhinella arenarum (Amphibia: Anura). Gen Comp Endocrinol. 2012 May 1. doi:10.1016/j.ygcen.2012.01.004 | PubMed

Tokuda K, Izumi Y, Zorumski CF. Ethanol enhances neurosteroidogenesis in hippocampal pyramidal neurons by paradoxical NMDA receptor activation. J Neurosci. 2011 Jul 6. doi:10.1523/JNEUROSCI.1660-11.2011 | PubMed | PMC full text

van Luijtelaar G, Budziszewska B, Tetich M, Lasoń W. Finasteride inhibits the progesterone-induced spike-wave discharges in a genetic model of absence epilepsy. Pharmacol Biochem Behav. 2003 Jul. doi:10.1016/s0091-3057(03)00162-x | PubMed

Ophthalmology

See also: Bibliography on ocular toxicity

Fusi-Rubiano W, Saedon H, Patel V, Yang YC. Oral medications for central serous chorioretinopathy: a literature review. Eye (Lond). 2020 May. DOIPubMedPMC full text

Gülkaş S, Şahin Ö. Current Therapeutic Approaches to Chronic Central Serous Chorioretinopathy. Turk J Ophthalmol. 2019 Feb 28. DOI • PubMedPMC full text

Moisseiev E, Holmes AJ, Moshiri A, Morse LS. Finasteride is effective for the treatment of central serous chorioretinopathy. Eye (Lond). 2016 Jun. DOIPubMedPMC full text

Pharmacology & biochemistry

Agis-Balboa RC, Guidotti A, Pinna G. 5α-reductase type I expression is downregulated in the prefrontal cortex/Brodmann’s area 9 (BA9) of depressed patients. Psychopharmacology (Berl). 2014 Sep. doi:10.1007/s00213-014-3567-5 | PubMed | PMC full text

Bortolato M, Frau R, Orrù M, et al. Antipsychotic-like properties of 5-alpha-reductase inhibitors. Neuropsychopharmacology. 2008 Dec. doi:10.1038/npp.2008.39 | PubMed

Bosse GD, Cadeddu R, Floris G, et al. The 5α-reductase inhibitor finasteride reduces opioid self-administration in animal models of opioid use disorder. J Clin Invest. 2021 Apr 13. doi:10.1172/JCI143990 | PubMed

Bull HG, Garcia-Calvo M, Andersson S, et al. Mechanism-Based Inhibition of Human Steroid 5α-Reductase by Finasteride:  Enzyme-Catalyzed Formation of NADP−Dihydrofinasteride, a Potent Bisubstrate Analog Inhibitor. Journal of the American Chemical Society. 1996. doi:10.1021/ja953069t

Devoto P, Frau R, Bini V, et al. Inhibition of 5α-reductase in the nucleus accumbens counters sensorimotor gating deficits induced by dopaminergic activation. Psychoneuroendocrinology. 2012 Oct. doi:10.1016/j.psyneuen.2011.09.018 | PubMed | PMC full text

Eckstein M, Rea M, Fondufe-Mittendorf YN. Transient and permanent changes in DNA methylation patterns in inorganic arsenic-mediated epithelial-to-mesenchymal transition. Toxicol Appl Pharmacol. 2017 Sep 15. doi:10.1016/j.taap.2017.03.017 | PubMed | PMC full text

Ellsworth KP, Azzolina BA, Cimis G, Bull HG, Harris GS. Cloning, expression and characterization of rhesus macaque types 1 and 2 5alpha-reductase: evidence for mechanism-based inhibition by finasteride. J Steroid Biochem Mol Biol. 1998 Sep. doi:10.1016/s0960-0760(98)00059-4 | PubMed

Finn DA, Long SL, Tanchuck MA, Crabbe JC. Interaction of chronic ethanol exposure and finasteride: sex and strain differences. Pharmacol Biochem Behav. 2004 Jul. doi:10.1016/j.pbb.2004.04.016 | PubMed

Fouad Mansour M, Pelletier M, Tchernof A. Characterization of 5α-reductase activity and isoenzymes in human abdominal adipose tissues. J Steroid Biochem Mol Biol. 2016 Jul. doi:10.1016/j.jsbmb.2016.02.003 | PubMed

Frau R, Pillolla G, Bini V, Tambaro S, Devoto P, Bortolato M. Inhibition of 5α-reductase attenuates behavioral effects of D1-, but not D2-like receptor agonists in C57BL/6 mice. Psychoneuroendocrinology. 2013 Apr. doi:10.1016/j.psyneuen.2012.07.014 | PubMed

Han Y, Zhuang Q, Sun B, et al. Crystal structure of steroid reductase SRD5A reveals conserved steroid reduction mechanism. Nat Commun. 2021 Jan 19. doi:10.1038/s41467-020-20675-2 | PubMed

Ishii Y, Mukoyama H, Hata S. Metabolism of finasteride in rat hepatic microsomes: age and sex differences and effects of P450 inducers. Xenobiotica. 1994 Sep. doi:10.3109/00498259409043285 | PubMed

Khantham C, Yooin W, Sringarm K, et al. Effects on Steroid 5-Alpha Reductase Gene Expression of Thai Rice Bran Extracts and Molecular Dynamics Study on SRD5A2. Biology (Basel). 2021 Apr 11. doi:10.3390/biology10040319 | PubMed

Kim D, Cho H, Eggers R, Kim SK, Ryu CS, Kim YJ. Development of a Liquid Chromatography/Mass Spectrometry-Based Inhibition Assay for the Screening of Steroid 5-α Reductase in Human and Fish Cell Lines. Molecules. 2021 Feb 8. doi:10.3390/molecules26040893 | PubMed

Kim HJ, Kim TJ, Kim YG, Seong C, Cho JH, Kim W, Lee KH, Kim DY. Antioxidant and Antiproliferative Activity of Finasteride against Glioblastoma Cells. Pharmaceutics. 2021 Sep 6. doi:10.3390/pharmaceutics13091410 | PubMed

Kudryashov NV, Ivanova EA, Kalinina TS, et al. Antiexudative Effects of Finasteride and a New Pyrazolo[C]Pyridine Derivative GIZh-72 in Acetic Acid-Induced Experimental Peritonitis. Bull Exp Biol Med. 2020 Feb. doi:10.1007/s10517-020-04730-y | PubMed

Olayinka ET, Adewole KE. Ameliorative effect of morin on dutasteride-tamsulosin-induced testicular oxidative stress in rat. J Complement Integr Med. 2020 Dec 23. doi:10.1515/jcim-2019-0160 | PubMed

Paba S, Frau R, Godar SC, Devoto P, Marrosu F, Bortolato M. Steroid 5α-reductase as a novel therapeutic target for schizophrenia and other neuropsychiatric disorders. Curr Pharm Des. 2011. doi:10.2174/138161211795049589 | PubMed

Peng HM, Valentín-Goyco J, Im SC, et al. Expression in Escherichia Coli, Purification, and Functional Reconstitution of Human Steroid 5α-Reductases. Endocrinology. 2020 Aug 1. doi:10.1210/endocr/bqaa117 | PubMed

Psychiatry & Neurology

Bortolato M, Cannas A, Solla P, Bini V, Puligheddu M, Marrosu F. Finasteride attenuates pathological gambling in patients with Parkinson disease. J Clin Psychopharmacol. 2012 Jun. doi:10.1097/JCP.0b013e3182549c2a | PubMed

Bortolato M, Muroni A, Marrosu F. Treatment of Tourette’s syndrome with finasteride. Am J Psychiatry. 2007 Dec. doi:10.1176/appi.ajp.2007.07060978 | PubMed

Koethe D, Bortolato M, Piomelli D, Leweke FM. Improvement of general symptoms in a chronic psychotic patient treated with finasteride: case report. Pharmacopsychiatry. 2008 May. doi:10.1055/s-2008-1058110 | PubMed. Erratum in: Pharmacopsychiatry. 2011 Jun;44(4):163.

Sports medicine

Iannella L, Colamonici C, Curcio D, et al. 5α-reductase inhibitors: Evaluation of their potential confounding effect on GC-C-IRMS doping analysis. Drug Test Anal. 2021 Jul 27. doi:10.1002/dta.3134 | PubMed

Urology

Bartsch G, Rittmaster RS, Klocker H. Dihydrotestosterone and the concept of 5alpha-reductase inhibition in human benign prostatic hyperplasia. World J Urol. 2002 Apr. doi:10.1007/s00345-002-0248-5 | PubMed

Häggström S, Tørring N, Møller K, et al. Effects of finasteride on vascular endothelial growth factor. Scand J Urol Nephrol. 2002. doi:10.1080/003655902320131848 | PubMed

Kuhlmann PK, Fischer SC, Howard LE, et al. Dutasteride Improves Nocturia but Does Not Lead to Better Sleep: Results from the REDUCE Clinical Trial. J Urol. 2021 Jun. doi:10.1097/JU.0000000000001640 | PubMed

Luo LM, Yang RD, Wang JM, et al. Association between 5α-reductase inhibitors therapy and incidence, cancer-specific mortality, and progression of prostate cancer: evidence from a meta-analysis. Asian J Androl. 2020 Sep-Oct. doi:10.4103/aja.aja_112_19 | PubMed | PMC full text

Mizoguchi S, Mori K, Shin T, Wang Z, DeFranco DB, Yoshimura N, Mimata H. Effects of dutasteride in a rat model of chemically induced prostatic inflammation-Potential role of estrogen receptor β. Prostate. 2020 Dec. doi:10.1002/pros.24071 | PubMed

Zhang B, Chen X, Liu YH, et al. Periprostatic fat thickness measured on MRI correlates with lower urinary tract symptoms, erectile function, and benign prostatic hyperplasia progression. Asian J Androl. 2021 Jan-Feb. doi:10.4103/aja.aja_51_20 | PubMed | PMC full text

Zhang XH, Hu LQ, Zheng XM, Li SW. Apoptosis in rat erectile tissue induced by castration. Asian J Androl. 1999 Dec. PubMed | Journal full text

Zhu D, Srivastava A, Agalliu I, et al. Finasteride Use and Risk of Bladder Cancer in a Multiethnic Population. J Urol. 2021 Jul. doi:10.1097/JU.0000000000001694 | PubMed