Merck and the Vioxx debacle

Vioxx debacle

Book

Nesi T. Poison Pills: The Untold Story of the Vioxx Drug Scandal. 2008; Thomas Dunne Books.

Government hearing

Graham, David J. Testimony at: FDA, Merck and Vioxx: Putting Patient Safety First? A hearing of the United States Senate Finance Committee. November 18, 2004. Text • Hearing agenda & documents

Journal articles

Hill KP, Ross JS, Egilman DS, Krumholz HM. The ADVANTAGE seeding trial: a review of internal documents. Ann Intern Med. 2008. DOI • PubMed

Horton R. Vioxx, the implosion of Merck, and aftershocks at the FDA. Lancet. 2004. doi:10.1016/S0140-6736(04)17523-5 • PubMed

Krumholz HM, Ross JS, Presler AH, Egilman DS. What have we learnt from Vioxx? BMJ. 2007. DOI • PubMed • PMC full text

Ross JS, Hill KP, Egilman DS, Krumholz HM. Guest authorship and ghostwriting in publications related to rofecoxib: a case study of industry documents from rofecoxib litigation. JAMA. 2008. DOI • PubMed

Media coverage

Giles J. Drug giant Merck accused of deaths cover-up. New Scientist. April 15, 2008.

Grifo F. Vioxx shows what happens when the drug safety system breaks down. The Equation, a blog of the Union of Concerned Scientists. March 19, 2012.

Leung R. Prescription for Trouble. 60 Minutes. November 14, 2004.

Merck manipulated the science about the drug Vioxx. Case study of the Union of Concerned Scientists. October 12, 2017.

Rubin R. How did Vioxx debacle happen? USA TODAY. October 11, 2004.

Simons J. Will Merck survive Vioxx? Fortune. November 1, 2004.

Vioxx: The Downfall of a Drug. NPR Special Series. June 10, 2005–November 10, 2007.

History of Merck

Bernschneider-Reif, Sabine, Walter Th. Huber & Ingunn Possehl. “Was der Mensch thun kann…”: History of the Pharmaceutical and Chemical Company Merck. 2002; Merck.

Burhop, Carsten. Merck: From a Pharmacy to a Global Corporation, 1668-2018. 2018; C. H. Beck.

Galambos, Louis. Networks of Innovation: Vaccine Development at Merck, Sharp & Dohme, and Mulford, 1895-1995. 1995; Cambridge University Press.

Galambos, Louis & Merck & Co. Values & Visions: A Merck Century. 1991; Merck & Co.

Merck, E. A History of Chemical Achievement, 1827-1937. 1937.

O’Callaghan, Jerry. The Red Book: The Hanrahan Case Against Merck, Sharp, and Dohme. 1992; Poolbeg.