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da Cruz GK, Martins MIM, Antunes FTT, et al. Evaluation of the efficacy and toxicity of oral and topical pumpkin oil on the hair growth of mice. Acta Histochem. 2022 Apr 18. doi:10.1016/j.acthis.2022.151894 • PubMed

“Minoxidil increased the DNA damage in the blood and the liver tissues.”

Donovan DJ. Paresthesias from topical minoxidil: Are we missing it? Donovan Hair Clinic [dermatologist’s blog post]. donovanmedical.com/hair-blog/minoxidil-paresthesias

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Minoxidil has “demonstrated preclinical drug-induced vascular injury but lack[s] clinical evidence… [M]inoxidil demonstrated minor endothelial cell barrier injury but damaged vascular smooth muscle cells…”

Hsu CL, Liu JS, Lin AC, Yang CH, Chung WH, Wu WG. Minoxidil may suppress androgen receptor-related functions. Oncotarget. 2014 Apr 30. doi:10.18632/oncotarget.1886 • PubMed • PMC full text

Korbi M, Said El Mabrouk R, Abdelaali M, Youssef M, Belhadjali H, Zili J. Topical minoxidil-induced paresthesia. Dermatol Ther. 2022 Apr. doi:10.1111/dth.15328 • PubMed

Mazen A. Topical minoxidil 5% induced male sexual dysfunction. Indian Journal of Medical Research and Pharmaceutical Sciences [not indexed in PubMed]. 2017 May. doi:10.5281/zenodo.580856

Mir-Bonafé JF, Mir-Bonafé M, Rozas-Muñoz E, Mir-Bonafé JM. Morning periorbital edema related to low-dose oral minoxidil. Actas Dermosifiliogr. 2022 Apr 28. English, Spanish. doi:10.1016/j.ad.2021.09.010 • PubMed • PDF in English (automated translation) • PDF in Spanish

Moreno-Arrones OM, Rodrigues-Barata R, Morales C, et al. Serious adverse effects from compounding errors with low-dose oral minoxidil for alopecia treatment. Actas Dermosifiliogr. 2022. English, Spanish. doi:10.1016/j.ad.2021.03.003PubMed

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