Post-SSRI sexual dysfunction

See also bibliographies at PSSD Network, the Canadian PSSD SocietyPSSD Hilfe (bottom of page) and other PSSD associations.

Bahrick AS. Post SSRI sexual dysfunction. Am Soc Advan Pharmacother Tablet. 2006 Sep;7(3): 2–3, 10–11.

Bala A, Nguyen HMT, Hellstrom WJG. Post-SSRI sexual dysfunction: a literature review. Sex Med Rev. 2018. doi:10.1016/j.sxmr.2017.07.002 • PubMed

Ben-Sheetrit J, Hermon Y, Birkenfeld S, Gutman Y, Csoka AB, Toren P. Estimating the risk of irreversible post-SSRI sexual dysfunction (PSSD) due to serotonergic antidepressants. Ann Gen Psychiatry. 2023. doi:10.1186/s12991-023-00447-0PubMed • PMC full text

Bolton JM, Sareen J, Reiss JP. Genital anaesthesia persisting six years after sertraline discontinuation. J Sex Marital Ther. 2006. doi:10.1080/00926230600666410PubMed

Chinchilla Alfaro K, van Hunsel F, Ekhart C. Persistent sexual dysfunction after SSRI withdrawal: a scoping review and presentation of 86 cases from the Netherlands. Expert Opin Drug Saf. 2022. doi:10.1080/14740338.2022.2007883• PubMed

Csoka AB, Shipko S. Persistent sexual side effects after SSRI discontinuation. Psychother Psychosom. 2006. doi:10.1159/000091777 • PubMed

De Luca R, Bonanno M, Manuli A, Calabrò RS. Cutting the first turf to heal post-SSRI sexual dysfunction: a male retrospective cohort study. Medicines (Basel). 2022. doi:10.3390/medicines9090045 • PubMed • PMC full text

Ekhart GC, van Puijenbroek EP. Blijvende seksuele functiestoornissen na staken van een SSRI? [Does sexual dysfunction persist upon discontinuation of selective serotonin reuptake inhibitors?]. Tijdschr Psychiatr. 2014. Dutch. PubMedJournal site

Giatti S, Diviccaro S, Panzica G, Melcangi RC. Post-finasteride syndrome and post-SSRI sexual dysfunction: two sides of the same coin? Endocrine. 2018. doi:10.1007/s12020-018-1593-5 • PubMed

Healy D. Antidepressants and sexual dysfunction: a history. J R Soc Med. 2020. doi:10.1177/0141076819899299 • PubMed

Healy D. Post-SSRI sexual dysfunction & other enduring sexual dysfunctions. Epidemiol Psychiatr Sci. 2020. doi:10.1017/S2045796019000519 • PubMed • PMC full text

Healy D, Bahrick A, Bak M, et al. Diagnostic criteria for enduring sexual dysfunction after treatment with antidepressants, finasteride and isotretinoin. Int J Risk Saf Med. 2021. doi:10.3233/JRS-210023 • PubMed

Hellmann-Regen J, Uhlemann R, Regen F, et al. Direct inhibition of retinoic acid catabolism by fluoxetine. J Neural Transm (Vienna). 2015 Sep. doi:10.1007/s00702-015-1407-3 • PubMed

Montejo AL, Llorca G, Izquierdo JA, et al. Disfunción sexual con antidepresivos. Efecto del cambio a amineptino en pacientes con disfunción sexual secundaria a ISRS [Sexual dysfunction with antidepressive agents. Effect of the change to amineptine in patients with sexual dysfunction secondary to SSRI]. Actas Esp Psiquiatr. 1999;27(1):23-34. PubMed

Reisman Y. Post-SSRI sexual dysfunction. BMJ. 2020 Feb 27;368:m754. doi:10.1136/bmj.m754 • PubMed

Rothmore J. Antidepressant-induced sexual dysfunction. Med J Aust. 2020 Apr;212(7):329-334. doi:10.5694/mja2.50522 • PubMed

Studt A, Gannon M, Orzel J, Vaughan A, Pearlman AM. Characterizing post-SSRI sexual dysfunction and its impact on quality of life through an international online survey. Int J Risk Saf Med. 2021. doi:10.3233/JRS-210039 • PubMed

Waldinger MD, van Coevorden RS, Schweitzer DH, Georgiadis J. Penile anesthesia in post SSRI sexual dysfunction (PSSD) responds to low-power laser irradiation: a case study and hypothesis about the role of transient receptor potential (TRP) ion channels. Eur J Pharmacol. 2015. doi:10.1016/j.ejphar.2014.11.031 • PubMed