Other systems & functions

See also: Cancer risk

Blood

Al-Harbi TM, Kagan J, Tarnopolsky MA. Finasteride-induced myalgia and HyperCKemiaJ Clin Neuromuscul Dis. 2008. doi:10.1097/CND.0b013e3181873cca • PubMed

Kouriefs C, Betambeau N, Rowbotham C, Coyne K, Rowley M, Jones CR. Finasteride-induced thrombocytopeniaBJU Int. 2002. doi:10.1046/j.1464-410x.2002.02851.x • PubMed

Smith VM, Cockshoot D. A serious side effect of a potentially widely used cosmetic product. Clin Exp Dermatol. 2015. doi:10.1111/ced.12570 • PubMed [Rhabdomyolysis]

Cytology

Zimmerman RL, Fogt F, Cronin D, Lynch R. Cytologic atypia in a 53-year-old man with finasteride-induced gynecomastia. Arch Pathol Lab Med. 2000. doi:10.5858/2000-124-0625-CAIAYO • PubMed

Dental adverse effects

Paunica S, Giurgiu M, Vasilache A, et al. Finasteride adverse effects and post-finasteride syndrome; implications for dentists. Journal of Mind and Medical Sciences. 2016. Journal site. Accessed May 14, 2021.

DNA damage & effects

See also: Research by field: Genetics & epigenetics and Special topics: DNA repair

Albasher G, Bin-Jumah M, Alfarraj S, et al. Prolonged use of finasteride-induced gonadal sex steroids alterations, DNA damage and menstrual bleeding in women. Biosci Rep. 2020. doi:10.1042/BSR20191434 • PubMedPMC full text

Alkahtane AA, Albasher G, Al-Sultan NK, et al. Long-term treatment with finasteride induces apoptosis and pathological changes in female mice. Hum Exp Toxicol. 2019. doi:10.1177/0960327119842195PubMed

Angrimani DSR, Bicudo LC, Llamas Luceño N, et al. Does finasteride treatment for benign prostatic hyperplasia influence sperm DNA integrity in dogs? Basic Clin Androl. 2020. doi:10.1186/s12610-020-00108-2 • PubMed

Rittmaster RS, Magor KE, Manning AP, Norman RW, Lazier CB. Differential effect of 5 alpha-reductase inhibition and castration on androgen-regulated gene expression in rat prostate. Mol Endocrinol. 1991. doi:10.1210/mend-5-7-1023 • PubMed

Tu HY, Zini A. Finasteride-induced secondary infertility associated with sperm DNA damage. Fertil Steril. 2011. doi:10.1016/j.fertnstert.2010.12.061 • PubMed

Microbiome

Borgo F, Macandog AD, Diviccaro S, et al. Alterations of gut microbiota composition in post-finasteride patients: a pilot study. J Endocrinol Invest. 2021 Jun. doi:10.1007/s40618-020-01424-0PubMed • PMC full text

Diviccaro S, Giatti S, Borgo F, et al. Treatment of male rats with finasteride, an inhibitor of 5alpha-reductase enzyme, induces long-lasting effects on depressive-like behavior, hippocampal neurogenesis, neuroinflammation and gut microbiota composition. Psychoneuroendocrinology. 2019. doi:10.1016/j.psyneuen.2018.09.021 • PubMed

Liu J, Lai L, Lin J, et al. Ranitidine and finasteride inhibit the synthesis and release of trimethylamine N-oxide and mitigates its cardiovascular and renal damage through modulating gut microbiota. Int J Biol Sci. 2020 Jan 14. doi:10.7150/ijbs.40934 • PubMed

Sleep

Gupta MA, Vujcic B, Gupta AK. Finasteride use is associated with higher odds of obstructive sleep apnea: results from the US Food and Drug Administration Adverse Events Reporting System. Skinmed. 2020 May 1;18(3):146-150. Via journal site • PubMed

Gupta MA, Vujcic B, Sheridan AD, Gupta AK. 0917 Finasteride is associated with a higher odds of obstructive sleep apnea (OSA): results from the US FDA Adverse Events Reporting System (FAERS). Sleep. 2018 Apr;41(Suppl 1). doi:10.1093/sleep/zsy061.916

Tinnitus & deafness

Rogers R. Re: Tinnitus and deafness: rare finasteride side effects [Letter]. Hair Transplant Forum International. 2010. doi:10.33589/20.2.0068