Physicians have used flimsy arguments to cast doubt on 5-alpha syndrome. They overlook social context, misread literature, omit inconvenient facts and disparage patients. Rebuttals for each of these arguments are provided.
The clear and concerning results in this abstract are statistically significant RORs for suicidal and self-injurious behaviors, anxiety disorders and depressed mood disorders in the finasteride-only group. The suggestion that combination therapy could “decrease” risk or have a “protective” role is unwarranted because the risk ratios are derived from unrelated sets of cases. This study seems to treat pharmacovigilance data as if it were a controlled, prospective study, when the data is uncontrolled and retrospective.